已验证应用 : 酶联免疫吸附实验 (ELISA)稀释倍数 : Assay dependent种属反应 : Virus宿主/亚型 : Mouse / IgM分类 : Monoclonal类型 : Antibody克隆号 : S-13抗原 : Synthetic peptide of at least 30 residues from gene encoding ORF3 region of a Chinese HEV strain偶联物 : Unconjugated形式 : Liquid浓度 : 1 mg/mL纯化类型 : Antigen affinity chromatography保存液  : PBS, pH 7.2内含物 : no preservative保存条件 : Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.RRID : AB_559443

Catalog Number:790-2991Quantity:790-100 Kit (US ONLY)kit includes: PATHWAY HER-2/neu (4B5) Primary Antibody (50 tests), PATHWAY HER-2 4in1 Control Slides (10), Interpretation Guide</small>790-2991 Antibody ONLY (outside US) 50 testsControls:Breast CarcinomaClone Name:4B5Species:RabbitLocalization:MembranousRegulatory Status:IVDThis antibody is intended for in vitro diagnostic use. Ventana Medical Systems, Inc. (Ventana) PATHWAY anti-HER-2/neu (4B5) Rabbit Monoclonal Primary Antibody (PATHWAY HER2 (4B5)) is a rabbit monoclonal antibody intended for laboratory use for the semi-quantitative detection of HER2 antigen in sections of formalin-fixed, paraffin-embedded normal and neoplastic tissue on a VENTANA automated immunohistochemistry slide staining device. It is indicated as an aid in the assessment of breast cancer patients for whom Herceptin treatment is considered. Note: All of the patients in the Herceptin clinical trials were selected using a clinical trial assay. None of the patients in those trials were selected using PATHWAY anti-HER-2/neu (4B5). PATHWAY anti-HER-2/neu (4B5) was compared to PATHWAY HER-2 (clone CB11) Primary Antibody on an independent sample set and found to provide acceptably concordant results. The actual correlation of PATHWAY anti-HER-2/neu (4B5) to clinical outcome has not been established. The VIAS Image Analysis System is an adjunctive optional computer-assisted image analysis system functionally connected to an interactive microscope. It is intended for use as an aid to the pathologist in the detection, classification and counting of cells of interest based on marker intensity, size and shape using appropriate controls to assure the validity of the VIAS scores. Prescription use only.

The 9D9 monoclonal antibody reacts with mouse CTLA-4 (cytotoxic T lymphocyte antigen-4) also known as CD152. CTLA-4 is a 33 kDa cell surface receptor encoded by the Ctla4 gene that belongs to the CD28 family of the Ig superfamily. CTLA-4 is expressed on activated T and B lymphocytes. CTLA-4 is structurally similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to the B7 family members B7-1 (CD80) and B7-2 (CD86). Upon ligand binding, CTLA-4 negatively regulates cell-mediated immune responses. CTLA-4 plays roles in induction and/or maintenance of immunological tolerance, thymocyte development, and regulation of protective immunity. The critical role of CTLA-4 in immune down-regulation has been demonstrated in CTLA-4 deficient mice, which succumb at 3-5 weeks of age due to the development of a lymphoproliferative disease. CTLA-4 is among a group of inhibitory receptors being explored as cancer treatment targets through immune checkpoint blockade.ImmunogenNot available or unknownReported Applicationsin vivo CTLA-4 neutralizationWestern blotEndotoxin<1EU/mg (<0.001EU/μg)Determined by LAL gel clotting assayBinding ValidationDetermined by immunoblotPurity>95%Determined by SDS-PAGEAggregation<5%Determined by DLSFormulationPBS, pH 7.0Contains no stabilizers or preservativesSterility0.2 μM filteredProductionPurified from tissue culture supernatant in an animal free facilityPurificationProtein AStorageThe antibody solution should be stored undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.Murine Pathogen Test ResultsMouse Norovirus: NegativeMouse Parvovirus: NegativeMouse Minute Virus: NegativeMouse Hepatitis Virus: NegativeReovirus Screen: NegativeLymphocytic Choriomeningitis virus: NegativeLactate Dehydrogenase-Elevating Virus: NegativeMouse Rotavirus: NegativeTheiler's Murine Encephalomyelitis: NegativeEctromelia/Mousepox Virus: NegativeHantavirus: NegativePolyoma Virus: NegativeMouse Adenovirus: NegativeSendai Virus: NegativeMycoplasma Pulmonis: NegativePneumonia Virus of Mice: NegativeMouse Cytomegalovirus: NegativeK Virus: NegativeRRIDAB_10949609