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  • 激酶筛选与分析

    激酶筛选与分析

    通过选择我们600多种激酶的任意组合创建您自己的激酶分析,或选择我们的每月激酶组:Wild Type Kinase Panel (376 Kinases)  Mutant Kinase Panel  (233 Kinases)   Atypical Kinase Panel (24 Kinases)  Lipid Kinase Panel (17 Kinases)  All Kinase Assays  (Full Kinase Panel: 650)备注:一个化合物一个靶点 1200元, 一个阳性对照 600元,(化合物寄往美国的运费按实际收取,实验周期详询)。服务: 大规模高通量筛选试验   大规模单剂量,重复分析服务       IC50分析服务 - 曲线拟合5或10剂量      ATP - 竞争性评估测定服务     化合物结合可逆性测试     Ki测定分析服务     定制分析开发      底物测定试验     Kinase Assays: 600+ Kinases Assays Available for HTS and ProfilingABL1ABL; JTK7; p150; c-ABL; v-ablABL1 (E255K)ABL1 (E255K)ABL1 (E255V)ABL1 (E255V)ABL1 (F317I)ABL1 (F317I)ABL1 (F317L)ABL1 (F317L)ABL1 (G160L)ABL1 (G160L)ABL1 (G250E)ABL1 (G250E)ABL1 (H396P)ABL1 (H396P)ABL1 (M351T)ABL1 (M351T)ABL1 (Q252H)ABL1 (Q252H)ABL1 (T315I)ABL1 (T315I)ABL1 (V299L)ABL1 (V299L)ABL1 (Y253F)ABL1 (Y253F)ABL1 (Y253H)ABL1 (Y253H)ABL2/ARGABLLACK1TNK2; p21cdc42Hs; Activated CDC42 kinase 1AKT1PKB; RAC; PRKBA; RAC-ALPHAAKT1 (E17K)AKT1AKT2PRKBB; PKBBETA; RAC-BETAAKT2 (E17K)AKT2AKT3PKBG; PRKBG; STK-2; RAC-gamma; RAC-PK-gammaAKT3 (E17K)AKT3 (E17K)AKT3 (G171R)AKT3ALKCD246; NBLST3ALK (C1156Y)ALK (C1156Y)ALK (F1174L)ALK (F1174L)ALK (F1174L)-EML4EML4-ALK (F1174L) fusionALK (F1174L)-NPM1NPM1-ALK (F1174L) fusionALK (F1174S)ALK (F1174S)ALK (G1202R)ALK (G1202R)ALK (G1269A)ALK (G1269A)ALK (G1269S)ALK (G1269S)ALK (L1152R)ALK (L1152R)ALK (R1275Q)ALK (R1275Q)ALK (S1206R)ALK (S1206R)ALK (T1151-L1152insT)ALK (T1151-L1152insT)ALK (T1151M)ALK (T1151M)ALK(L1196M)ALK (L1196M)ALK1/ACVRL1ACVRLK1; ALK-1; ALK1; HHT; HHT2; ORW2; SKR3ALK2 (Q207D)ACVR1ALK2 (R206H)ACVR1ALK2/ACVR1ACTRI; ACVRLK2; SKR1ALK3/BMPR1A10q23del; ACVRLK3; CD292; SKR5ALK4/ACVR1BACTRIB; ACVRLK4; ALK4; SKR2ALK5/TGFBR1SKR4ALK6/BMPR1BBMR1BALK-KIF5B (Kex24Aex20)KIF5B-ALK (Kex24Aex20)ALK-KLC1 (Kex8Aex20)KLC1-ALK (Kex8Aex20)ALK-NPM1ALK-NPM1ALK-TFGTFG-ALK fusionALK-TFG (Tex4Aex20)TFG-ALK (Tex4Aex20)ALK-TPM1TPM1-ALKALK-TPM3TPM3-ALK FusioinAMPK (A1/B1/G1)AMPK (A1/B1/G1)AMPK (A1/B1/G2)AMPK (A1/B1/G2)AMPK (A1/B1/G3)AMPK (A1/B1/G3)AMPK (A1/B2/G1)AMPK (A1/B2/G1)AMPK (A1/B2/G2)AMPK (A1/B2/G2)AMPK (A1/B2/G3)AMPK (A1/B2/G3)AMPK (A2/B1/G1)AMPK (A2/B1/G1)AMPK (A2/B1/G2)AMPK (A2/B1/G2)AMPK (A2/B1/G3)AMPK (A2/B1/G3)AMPK (A2/B2/G1)AMPK (A2/B2/G1)AMPK (A2/B2/G2)AMPK (A2/B2/G2)AMPK (A2/B2/G3)AMPK (A2/B2/G3)ARAFA-RA; ARAF1; PKS2; RAFA1ARK5/NUAK1ARK5/NUAK1ASK1/MAP3K5ASK1/MAP3K5Aurora AAurA; AURKA; AIK; ARK1; AURA; BTAK; STK15Aurora BAurB; AURKB; AIK2; AIM1; ARK2; AurB; IPL1; STK5;Aurora CAurC; AURKC; AIE2; AIK3; STK13AXLEC; UFOAXL (R499C)AXL (R499C)BLKBLKBMPR2BMPR-II; BMPR3; BMR2; BRK-3; PPH1; T-ALKBMX/ETKPSCTK2; PSCTK3BRAFB-Raf; B-raf-1; BRAF1; RAFB1BRAF (d485-489/P490Y)BRAF (d485-489/P490Y)BRAF (G464V)BRAF (G464V)BRAF (G469A)BRAF (G469A)BRAF (K601E)BRAF (K601E)BRAF (L597V)BRAF (L597V)BRAF (R506_K507insVLR)BRAF (R506_K507insVLR)BRAF (T599_V600insT)BRAF (T599_V600insT)BRAF (V599E)BRAF (V600E)BRAF (V600A)BRAF (V599A)BRAF (V600D)BRAF (V599D)BRAF (V600K)BRAF (V599K)BRAF-FAM131BFAM131B-BRAF fusionBRAF-KIAA1549 (Kex15Bex9)KIAA1549-BRAF (Kex15Bex9)BRAF-KIAA1549 (Kex16Bex9)KIAA1549-BRAF (Kex16Bex9)BRAF-SRGAP3 (Sex12Bex9)SRGAP3-BRAF (Sex12Bex9)BRKPTK6BRSK1KIAA1811BRSK2C11orf7; PEN11B; SAD1; STK29BTKAGMX1; AT; ATK; BPK; PSCTK1BTK (C481S)BTK (C481S), Bruton tyrosine kinaseBTK (P190K)BTK (P190K), Bruton tyrosine kinaseBTK(E41K)BTK(E41K)CAMK1aCAMK1; CAMK1-PEN; CAMKICAMK1bCAMK1b; PNCK; MGC45419CAMK1dCAMK1dCAMK1gCLICKIII; VWS1; dJ272L16.1CAMK2aCAMKA; KIAA0968; CAMK2ACAMK2bCAMK2B; CAM2; CAMK2; CAMKB; MGC29528CAMK2dCAMK2D; CAMKD; MGC44911; CaMKII deltaCAMK2gCAMK2G; CAMK; CAMK-II; CAMKG; MGC26678CAMK4CAMK4CAMKK1CAMKKA; DKFZp761M0423; MGC34095CAMKK2CAMKK; CAMKKB; KIAA0787; MGC15254CDC7/DBF4CDC7L1; HsCDC7; Hsk1; huCDC7CDK1/cyclin ACDK1/cyclin ACDK1/cyclin BCDK1/cyclin BCDK1/cyclin ECDK1/cyclin ECDK12 (R722C)/cyclin KCDK12 (R722C)/cyclin KCDK12/cyclin KCDK12/cyclin KCDK13/cyclin KCDK13/cyclin KCDK14/cyclin Y (PFTK1)CDK14/CCNYCDK16/cyclin YCDK16/cyclin Y, PCTAIRECDK17/cyclin YCDK17/cyclin Y, PCTK2CDK18/cyclin YCDK18/cyclin Y, PCTK3CDK19/cyclin CCDK19/cyclin CCDK2/cyclin ACDK2/cyclin A2CDK2/cyclin A1CDK2/cyclin A1CDK2/cyclin ECDK2/cyclin ECDK2/cyclin E2CDK2/cyclin E2CDK2/cyclin OCDK2/CCNOCDK3/cyclin ECDK3/cyclin ECDK3/cyclin E2CDK3/cyclin E2CDK4/cyclin D1CDK4/cyclin D1CDK4/cyclin D3CDK4/cyclin D3CDK5/p25CDK5/p25CDK5/p35CDK5/p35CDK6/cyclin D1CDK6/cyclin D1CDK6/cyclin D3CDK6/cyclin D3CDK7/cyclin HCDK7/cyclin HCDK8/cyclin CCDK8/cyclin CCDK9/cyclin KCDK9/cyclin KCDK9/cyclin T1CDK9/cyclin T1CDK9/cyclin T2CDK9/cyclin T2CHK1CHEK1CHK2CHEK2; CDS1; HuCds1; PP1425; RAD53CHK2(I157T)CHK2(I157T)CK1a1CK1a; CSNK1A1; CK1; HLCDGP1; PRO2975CK1a1LCSNK1A1LCK1dCSNK1D; HCKID; CK1-deltaCK1epsilonCK1e; CSNK1E; CKIe; HCKIE; MGC10398CK1epsilon (R178C)CK1epsilon (R178C)CK1g1CSNK1G1; CK1-gamma1CK1g2CSNK1G2; CK1-gamma2CK1g3CSNK1G3; CK1-gamma3CK2aCK2a1; CSNK2A1; CKII; CK2A1; CK2-alpha1CK2a2CK2a2; CSNK2A2; CK2-alpha2c-KITc-KITc-Kit (A829P)c-Kit (A829P)c-Kit (d557-558)c-Kit (d557-558)c-Kit (D816E)KITc-Kit (D816F)KITc-Kit (D816H)c-Kit (D816H)c-Kit (D816I)c-Kit (D816I)c-Kit (D816V)c-Kit (D816V)c-Kit (D816Y)KITc-Kit (D820E)c-Kit (D820E)c-Kit (D820Y)c-Kit (D820Y)c-Kit (K642E)c-Kit (K642E)C-Kit (T670I)C-Kit (T670I)c-Kit (V559A)c-Kit (V559A)c-Kit (V559D)c-Kit (V559D)c-Kit (V559D/T670I)c-Kit (V559D/T670I)c-Kit (V559D/V654A)c-Kit (V559D/V654A)C-Kit (V560G)C-Kit (V560G)C-Kit (V560G/D816V)C-Kit (V560G/D816V)c-Kit (V560G/N822K)c-Kit (V560G/N822K)c-Kit (V654A)c-Kit (V654A)c-Kit (Y823D)c-Kit (Y823D)CLK1CLK; CLK/STYCLK2MGC61500; clk2; hCLK2CLK3clk3; CDC-like kinase 3CLK4DKFZp686A20267; CDC-like kinase 4c-MERc-MERc-MER (A708S)c-MER (A708S)c-METc-METc-MET (D1228A)c-MET (D1228A)c-MET (D1228G)c-MET (D1228G)c-MET (D1228H)c-MET (D1228H)C-MET (D1228N)C-MET (D1228N)c-MET (D1228V)c-MET (D1228V)c-MET (D1228Y)c-MET (D1228Y)C-MET (F1200I)C-MET (F1200I)c-MET (G1163R)c-MET (G1163R)c-MET (H1094L)c-MET (H1094L)c-MET (H1094Y)c-MET (H1094Y)c-MET (K1244R)c-MET (K1244R)c-MET (L1195F)c-MET (L1195F)c-MET (M1250I)c-MET (M1250I)c-MET (M1250T)c-MET (M1250T)c-MET (P991S)c-MET (P991S)c-MET (T1173I)c-MET (T1173I)c-MET (T992I)c-MET (T992I)c-MET (V1092I)c-MET (V1092I)C-MET (Y1230A)C-MET (Y1230A)C-MET (Y1230C)C-MET (Y1230C)C-MET (Y1230D)C-MET (Y1230D)C-MET (Y1230H)C-MET (Y1230H)C-MET (Y1230S)C-MET (Y1230S)c-MET (Y1235D)c-MET (Y1235D)c-MET-KIF5B (Kex24Mex14)KIF5B-c-MET (Kex24Mex14) Fusion proteincMET-TFG (Tex5Mex15)TFG-cMET (Tex5Mex15)COT1/MAP3K8COT1/MAP3K8CSKCSKc-Srcc-Srcc-Src (T341M)c-Src (T341M)CTK/MATKCHK; CTK; HHYLTK; HYL;DAPK1DAPK1DAPK2DAPK2DCAMKL1DCLK1; DCLK; KIAA0369DCAMKL2DCLK2; DCDC3; DCK2; MGC45428DDR1CAK; CD167; DDR; EDDR1; MCK10; NEPDDR2MIG20a; NTRKR3; TKT; TYRO10DDR2 (N456S)DDR2 (N456S)DDR2 (T654M)DDR2 (T654M)DLK/MAP3K12MUK; ZPK; ZPKP1DMPKDMPK1; DM; DM1; DM1PK; DMKDMPK2/CDC42BPGDMPK2; HSMDPKIN; KAPPA-200;DNA-PKPRKDC; DNAPK; DNPK1; HYRC; p350DRAK1/STK17ADRAK1/STK17ADYRK1/DYRK1ADYRK; DYRK1; HP86; MNB; MNBHDYRK1BMIRKDYRK2DYRK2DYRK3DYRK5; RED; REDKDYRK4DYRK4EEF2KHSU93850; MGC45041; eEF-2KEGFRERBB; mENA; ERBB1EGFR (A763_Y764insFHEA)EGFR (A763_Y764insFHEA)EGFR (A763_Y764insFQEA)EGFR (A763_Y764insFQEA)EGFR (C775S /T790M /L858R)EGFR (C775S /T790M /L858R)EGFR (C797A)EGFR (C797A)EGFR (C797S /L858R)EGFR (C797S /L858R)EGFR (C797S)EGFR (C797S)EGFR (d746)EGFR (d746)EGFR (d746-750)EGFR (d746-750)EGFR (d746-750/C775S /T790M /L858R)EGFR (d746-750/C775S /T790M /L858R)EGFR (d746-750/C797A)EGFR (d746-750/C797A)EGFR (d746-750/C797S)EGFR (d746-750/C797S)EGFR (d746-750/T790M)EGFR (d746-750/T790M)EGFR (d746-750/T790M/C797S)EGFR (d746-750/T790M/C797S)EGFR (d747-749)EGFR (d747-749)EGFR (d747-749/A750P)EGFR (d747-749/A750P)EGFR (d747-752/P753S)EGFR (d747-752/P753S)EGFR (d752-759)EGFR (d752-759)EGFR (D761Y)EGFR (D761Y)EGFR (D770_N771insNPG)EGFR (D770_N771insNPG)EGFR (D770_N771insNPG/T790M)EGFR (D770_N771insNPG/T790M)EGFR (D770GY)EGFR (D770GY)EGFR (G719C)EGFR (G719C)EGFR (G719D)EGFR (G719D)EGFR (G719S)EGFR (G719S)EGFR (K716A)EGFR (K716A)EGFR (K716A/C797S/L858R)EGFR (K716A/C797S/L858R)EGFR (K716Q/L718Q)EGFR (K716Q/L718Q)EGFR (K728A)EGFR (K728A)EGFR (L718Q)EGFR (L718Q)EGFR (L747S)EGFR (L747S)EGFR (L792F)EGFR (L792F)EGFR (L792F/L858R)EGFR (L792F/L858R)EGFR (L792H/C797S/L858R)EGFR (L792H/C797S/L858R)EGFR (L858R)EGFR (L858R)EGFR (L858R,T790M)EGFR (L858R,T790M)EGFR (L861Q)EGFR (L861Q)EGFR (T790M)EGFR (T790M)EGFR (T790M/C797S /L858R)EGFR (T790M/C797S /L858R)EGFR (T790M/C797S)EGFR (T790M/C797S)EGFR (T790M/L792F/C797S/L858R)EGFR (T790M/L792F/C797S/L858R)EGFR (T790M/L792F/L858R)EGFR (T790M/L792F/L858R)EGFR (T790M/L792H/C797S/L858R)EGFR (T790M/L792H/C797S/L858R)EGFR (T790M/L792H/L858R)EGFR (T790M/L792H/L858R)EIF2AK1EIF2AK1EIF2AK2EIF2AK2EIF2AK3EIF2AK3EIF2AK4/GCN2EIF2AK4/GCN2EPHA1EPH; EPHT; EPHT1EPHA2ECKEPHA3ETK; ETK1; EphA3; HEKECK; HEK4; TYRO4EPHA4HEK8; SEK; TYRO1EPHA5CEK7; EHK1; EphA5; HEK7;EPHA6EPHA6EPHA7EHK3; EphA7; HEK11EPHA8EEK; EphA8; HEK3; KIAA1459EPHB1ELK; NET; Hek6; EPHT2EPHB2DRT; ERK; Hek5; EPHT3; Tyro5EPHB3ETK2; HEK2; TYRO6EPHB4HTK; MYK1; TYRO11ERBB2 (D769H)ERBB2 (D769H)ERBB2 (D769Y)ERBB2 (D769Y)ERBB2 (P1170A)ERBB2 (P1170A)ERBB2 (P780-Y781insGSP)ERBB2 (P780-Y781insGSP)ERBB2 (R896C)ERBB2 (R896C)ERBB2 (V777_G778insCG)HER2ERBB2 (V777L)ERBB2 (V777L)ERBB2/HER2NEU; NGL; HER2; TKR1; HER-2ERBB4/HER4ERBB4/HER4ERK1/MAPK3P44ERK1; P44MAPK; PRKM3ERK2/MAPK1ERK; ERT1; P42MAPK; PRKM1;ERK5/MAPK7 CDERK5/MAPK7 CDERK5/MAPK7 FLERK5/MAPK7ERK7/MAPK15ERK8ERN1/IRE1ERN1/IRE1ERN2/IRE2ERN2/IRE2FAK/PTK2FADK; pp125FAKFERTYK3FES/FPSFES/FPSFGFR1H2; H3; H4; H5; CEK; FLG; FLT2; KAL2FGFR1(V561M)FGFR1(V561M)FGFR1OP- FGFR1FGFR1OP- FGFR1 fusionFGFR2BEK; JWS; CEK3; CFD1; ECT1; KGFR;FGFR2 (C491A)FGFR2 (C491A)FGFR2 (C491F)FGFR2 (C491F)FGFR2 (C491S)FGFR2 (C491S)FGFR2 (E565G)FGFR2 (E565G)FGFR2 (K526E)FGFR2 (K526E)FGFR2 (K641R)FGFR2 (K641R)FGFR2 (K659N)FGFR2 (K659N)FGFR2 (N549H)FGFR2 (N549H)FGFR2 (R612T)FGFR2 (R612T)FGFR2 (V564F)FGFR2 (V564F)FGFR3ACH, CD333, CEK2, FGFR-3, HSFGFR3EXFGFR3 (G697C)FGFR3 (G697C)FGFR3 (K650E)FGFR3 (K650E)FGFR3 (K650M)FGFR3 (K650M)FGFR3 (K650Q)FGFR3 (K650Q)FGFR3 (V555M)FGFR3 (V555M)FGFR4TKF; JTK2; MGC20292FGFR4 (N535K)FGFR4 (N535K)FGFR4 (V550E)FGFR4 (V550E)FGFR4 (V550L)FGFR4 (V550L)FGFR4 (V550M)FGFR4 (V550M)FGRSRC2; c-fgr; p55c-fgrFLT1/VEGFR1FLT1/VEGFR1FLT3FLK2; STK1; CD135FLT3 (D835Y)FLT3 (D835Y)FLT3 (F594_R595insR)FLT3 (F594_R595insR)FLT3 (F594_R595insREY)FLT3 (F594_R595insREY)FLT3 (ITD)FLT3 (ITD)FLT3 (ITD)-NPOSFLT3 (ITD)-NPOSFLT3 (ITD)-W51FLT3 (ITD)-W51FLT3 (R595_E596insEY)FLT3 (R595_E596insEY)FLT3 (Y591_V592insVDFREYEYD)FLT3 (Y591_V592insVDFREYEYD)FLT4/VEGFR3PCLFMSCSF1RFRK/PTK5GTK; PTK5; RAKFYNMGC45350; SLK; SYNFYN (Y531F)FYN (Y531F)GCK/MAP4K2BL44; GCK; RAB8IPGLK/MAP4K3GLK/MAP4K3GRK1GRK1GRK2GRK2GRK3GRK3GRK4GPRK4; GPRK2L; GRK4a; IT11GRK5GPRK5GRK6GPRK6; FLJ32135GRK7GPRK7GSK3aGSK3-alphaGSK3bGSK3-betaHaspinGSG2HCKJTK9HGK/MAP4K4HGK/MAP4K4HIPK1KIAA0630; MGC26642; MGC33446; Myak; Nbak2HIPK2PRO0593HIPK3ANPK; DYRK6; FIST; FIST3; PKY; YAK1HIPK4FLJ32818HPK1/MAP4K1HPK1/MAP4K1IGF1RJTK13IKKa/CHUKIKBKA; IKK1; NFKBIKA; TCF16; IKK-alphaIKKb/IKBKBIKBKB; IKK2; IKKB; NFKBIKB; IKK-betaIKKe/IKBKEIKKI; IKK-i; KIAA0151; IKK-epsilonIRINSR, Ins receptorIRAK1PelleIRAK4REN64; NY-REN-64IRR/INSRRINSR-RITKEMT 2; LYK 2; PSCTK2 2JAK1JAK-1; JAK1A; AK1BJAK2JAK2JAK2 (V617F)JAK2 (V617F)JAK2 JH1&2JAK2 JH1&2JAK3JAKL; L-JAK; LJAKJNK1MAPK8; JNK; JNK1A2; JNK21B1/2; PRKM8JNK2MAPK9; JNK-55; JNK2A; JNK2ALPHA; JNK2B;JNK3MAPK10; JNK3A; PRKM10; p493F12KDR/VEGFR2FLK1; VEGFR; VEGFR2KHS/MAP4K5KHS1; GCKR; KHS; MAPKKKK5KSR1Kinase suppressor of Ras 1KSR1 (A635F)KSR1 (A635F)KSR1 (L639F)KSR1 (L639F)KSR2Kinase suppressor of Ras 2KSR2 (R676S)KSR2 (R676S)LATS1WARTS; wts; LATSLATS2FLJ13161; LATSLCKLCKLCK2/ICKLCK2/ICKLIMK1LIMK1LIMK2LIMK2LKB1LKB1LOK/STK10PRO2729LRRK2PARK8; ROCO2; FLJ45829;LRRK2 (G2019S)LRRK2 (G2019S)LRRK2 (I2020T)LRRK2 (I2020T)LRRK2 (R1441C)LRRK2 (R1441C)LYNJTK8LYNBLYNBMAKMAKMAPKAPK2MAPKAPK2MAPKAPK33PK; MAPKAP; MAPKAP3MAPKAPK5/PRAKMAPKAPK5/PRAKMARK1KIAA1477MARK2/PAR-1BaEMK1; MGC99619; PAR-1; ELKLMARK3CTAK1; KP78; PAR1AMARK4KIAA1860; MARKL1MAST3Microtubule-associated serine/threonine-protein kinase 3MASTLMicrotubule-associated serine/threonine-protein kinase-likeMEK1MEK1MEK1 (P124L)MEK1 (P124L)MEK2MEK2MEK3MAP2K3MEK5MAP2K5MEKK1MEKK1MEKK2MEKK2MEKK3MEKK3MEKK6MAP3K6, ASK2, MAPKKK6MELKKIAA0175MELK (T460M)MELK (T460M)MINK/MINK1MINK/MINK1MKK4MEK4MKK6MEK6MKK7MAP2K7MLCK/MYLKMLCK/MYLKMLCK2/MYLK2MLCK2/MYLK2MLK1/MAP3K9MLK1/MAP3K9MLK2/MAP3K10MLK2/MAP3K10MLK3/MAP3K11MLK3/MAP3K11MLK4MLK4MNK1MNK1MNK2MNK2MRCKa/CDC42BPAMRCK-alphaMRCKb/CDC42BPBMRCK-beta, MRCKbMSK1/RPS6KA5EC 2.7.11.,MGC1911, MSPK1,RLPK, RSKLMSK2/RPS6KA4RSK-B,MSSK1/STK23SRPK3, MGC102944MST1/STK4MST1/STK4MST2/STK3KRS1MST3/STK24MST-3; MST3B; STK3MST4MASKmTOR/FRAP1mTOR/FRAP1MUSKMUSKMYLK3MYLK3MYLK4Myosin light chain kinase family member 4MYO3AMyosin-IIIaMYO3bMYO3bNEK1KIAA1901; NY-REN-55;NEK11NEK11NEK2NLK1; HsPK21; HsPK 21NEK3HSPK36; MGC29949NEK4NRK2; STK2NEK5MGC75495NEK6SID6-1512NEK7NEK7NEK8NEK8NEK9DKFZp434D0935; MGC16714; NERCC;NIK/MAP3K14FTDCR1B; HS; HSNIKNIM1NIM1NLKNLKOSR1/OXSR1KIAA1101p38a(T106M)p38a(T106M)P38a/MAPK14p38-alpha; CSBP; CSBP1;P38b/MAPK11p38-beta; P38BETA2; PRKM11; SAPK2P38d/MAPK13p38-delta; PRKM13; SAPK4P38g/MAPK12p38-gamma; ERK-6; ERK3; ERK5; ERK6P70S6K/RPS6KB1S6K1; STK14AP70S6Kb/RPS6KB2KLS; P70-BETA; P70-beta-1; S6K-beta2PAK1PAKalphaPAK2PAK65; PAKgammaPAK3CDKN1A; MRX30; OPHN3; PAK3betaPAK4PAK4PAK5PAK7; KIAA1264; MGC26232PAK6PAK5PASKSTK3; DKFZP434O051; DKFZp686P2031PBK/TOPKSPK; Nori-3; FLJ14385PDGFRaPDGFR2; CD140aPDGFRa(D842V)PDGFRa(D842V)PDGFRa(T674I)PDGFRa(T674I)PDGFRa(V561D)PDGFRa(V561D)PDGFRa-FIP1L1FIP1L1-PDGFRa fusionPDGFRbJTK12; PDGFR; CD140B; PDGFR1PDGFRb-TPM3TPM3-PDGFRbPDK1/PDHK1PDK1/PDHK1PDK1/PDPK1PDK1/PDPK1PDK2/PDHK2PDK2/PDHK2PDK3/PDHK3PDK3/PDHK3PDK4/PDHK4PDK4/PDHK4PEAK1PEAK1PHKg1PHKg1PHKg2PHKg2PI3K (p110a(E542K)/p85a)PIK3CA/PIK3R1 mutantPI3K (p110a(E545K)/p85a)PIK3CA/PIK3R1 mutantPI3K (p110a(H1047R)/p85a)PIK3CA/PIK3R1 mutantPI3K (p110a/p65a)PIK3CA/PIK3R1PI3Ka (p110a/p85a)PIK3CA/PIK3R1PI3Kb (p110b/p85a)PIK3CB/PIK3R1PI3KC2aPIK3C2API3KC3PIK3C3, hVps34PI3Kd (p110d/p85a)PIK3CD/PIK3R1PI3Kg (p110g)PI3Kg (p120g), PIK3CGPI4K2AP4K2API4KaPIK4CAPI4KbPIK4CBPIM1PIM1PIM2PIM2PIM3PIM3PIP5K1APIP5K1APIP5K1CPIP5K1CPKAPKAPKAcbPRKACB; MGC41879; MGC9320; PKA C-betaPKAcgPKAcgPKCaPRKCA; PRKACA; PKC-alphaPKCb1PKCb1PKCb2PKCb2PKCdPRKCD; MAY1; MGC49908; nPKC-deltaPKCepsilonPKCe; PRKCE; nPKC-epsilonPKCetaPKCh; PRKCH; PKCL; PKC-L; PRKCLPKCgPRKCG; PKC-gamma; PKCC; PKCGPKCiotaPKCi; PRKCI; DXS1179E; MGC26534PKCmu/PRKD1PKD1; PKD; PKCM; PKC-MUPKCnu/PRKD3PKD3; EPK2; PKC-NU; PKD3; PRKCNPKCthetaPKCt; PRKCQ; PRKCT; nPKC-thetaPKCzetaPRKCZ; PKCz; PKC2PKD2 (G870E)PKD2 (G870E)PKD2/PRKD2HSPC187PKG1aPKG1aPKG1bPKG1bPKG2/PRKG2PRKGR2; cGKIIPKMYT1MYT1PKMzetaPKCzeta mutantPKN1/PRK1DBK; PKN; PAK1; PRK1; PRKCL1PKN1-TECR (Tex1Pex10)TECR-PKN1 (Tex1Pex10)PKN2/PRK2PKN2/PRK2PKN3/PRK3PKNbeta; RP11-545E17.1PLK1PLK; STPK13PLK2SNKPLK3CNK; FNK; PRKPLK4/SAKSAK; STK18PRKXPKX1PYK2PTK2B; CADTK, CAKB, FADK2; FAK2RAF1c-RAFRETPTC; MTC1; HSCR1; MEN2A; MEN2BRET (A883F)RET (A883F)RET (E762Q)RET (E762Q)RET (G691S)RET (G691S)RET (L790F)RET (L790F)RET (M918T)RET (M918T)RET (R749T)RET (R749T)RET (R813Q)RET (R813Q)RET (R912P)RET (R912P)RET (S891A)RET (S891A)RET (S904A)RET (S904A)RET (S904F)RET (S904F)RET (V778I)RET (V778I)RET (V804E)RET (V804E)RET (V804L)RET (V804L)RET (V804L)-KIF5BKIF5B-RET fusionRET (V804M)RET (V804M)RET (V804M)-KIF5BKIF5B-RET fusionRET (Y791F)RET (Y791F)RET (Y806H)RET (Y806H)RET-BCRBCR-RET fusionRET-CCDC6 (PTC1)CCDC6-RET fusion, PTC1RET-KIF5B (Kex15Rex14)KIF5B-RET fusionRET-NCOA4 (PTC3)NCOA4 -RET fusion, PTC3RET-PRKAR1A (PTC2)PRKAR1A-RET fusion, PTC2RIPK2CARD3; CARDIAK; RICK; RIP2RIPK3RIP3, receptor interacting protein 3RIPK4Receptor interacting protein kinase 4RIPK5RIPK5ROCK1P160ROCKROCK2KIAA0619; ROC2RON/MST1RCD136; CDw136; PTK8ROS/ROS1MCF3;ROS1 (G2032R)ROS1 (G2032R)ROS1-GOPCGOPC-ROS1 fusionROS1-TPM3TPM3-ROS1 fusionRSK1RPS6KA1; HU-2; MAPKAPK1A;RSK2RPS6KA3; HU-2; HU-3; ISPK-1; MAPKAPK1BRSK2 (I416V)RSK2 (I416V)RSK2 (L608F)RSK2 (L608F)RSK3RPS6KA2; HU-1; MAPKAPK1CRSK4RPS6KA6;SBK1SH3-binding kinase 1SGK1SGKSGK2H-SGK2; dJ138B7.2SGK3/SGKLCISK; SGK2; SGK3; SGKLSIK1SIK; MSK; SNF1LKSIK2SIK2SIK3SIK3SLK/STK2KIAA0204SNARK/NUAK2SNARK/NUAK2SNRKSNF1-related kinaseSPHK1Sphingosine kinase 1SPHK2Sphingosine kinase 2SRMSSRMSSRPK1SRPK1SRPK2SRPK2SSTK/TSSK6FLJ24002; SSTK; TSSK4STK16STK16STK21/CITSTK21/CIT, CRIKSTK22D/TSSK1STK22D/TSSK1STK25/YSK1STK25/YSK1STK32b/YANK2STK32b/YANK2STK32c/YANK3STK32c/YANK3STK33STK33STK38/NDR1STK38/NDR1STK38L/NDR2STK38L/NDR2STK39/STLK3STK39/STLK3SYKSYKTAK1MAP3K7; TGF1a; MEKK7TAOK1TAO1; KIAA1361; MAP3K16; MARKK;TAOK2/TAO1TAO2; MAP3K17; PSK; PSK1;TAOK3/JIKTAO3; DPK; JIK; MAP3K18TBK1CDC37; HSPCA; HSPCB; IKBKG; NAK; T2K;TECPSCTK4TESK1TESK1TESK2TESK2TGFBR2HNPCC6; MFS2; RIIC;TIE2 (A1124V)TIE2 (A1124V), TEKTIE2 (P883A)TIE2 (P883A)TIE2 (R849W)TIE2 (R849W)TIE2 (Y1108F)TIE2 (Y1108F)TIE2 (Y897C)TIE2 (Y897C)TIE2 (Y897S)TIE2 (Y897S)TIE2/TEKVMCM; TIE-2; VMCM1; CD202BTLK1PKU-beta; KIAA0137TLK2MGC44450; PKU-ALPHATNIKTNIKTNK1TNK1TRKANTRK1; MTC; TRK; TRK1TRKA (A608D)TRKA (A608D)TRKA (F589L)TRKA (F589L)TRKA (G595R)TRKA (G595R)TRKA (G595R/A608D)TRKA (G595R/A608D)TRKA (G595R/G667A)TRKA (G595R/G667A)TRKA (G595R/G667C)TRKA (G595R/G667C)TRKA (G595R/G667S)TRKA (G595R/G667S)TRKA (G595R/L657M)TRKA (G595R/L657M)TRKA (G667C)TRKA (G667C)TRKA (G667S)TRKA (G667S)TRKA (L657M)TRKA (L657M)TRKA-TFGTFG-TRKA fusionTRKA-TPM3TPM3-TRKA fusionTRKA-TPRTPR-TRKA fusionTRKBNTRK2; Trk-BTRKCNTRK3; Trk-C; gp145TRKC (G623E)TRKC (G623E)TRKC (G623R)TRKC (G623R)TRKC (G623R/L686M)TRKC (G623R/L686M)TRKC (G696A)TRKC (G696A)TRKC (L686M)TRKC (L686M)TRPM7/CHAK1TRPM7/CHAK1TSSK2DGS-G; 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  • 蛋白酶检测

    蛋白酶检测

    目前,有八种被批准用于治疗HIV感染的化合物,属于蛋白酶抑制剂。在所有类别的HIV药物中,蛋白酶抑制剂在药代动力学,药物相互作用和基于这些相互作用的剂量变化方面是*复杂的。除了HIV之外,蛋白酶抑制剂已经被批准用于治疗丙型肝炎,ACE抑制剂,正在研究与阿尔茨海默病,II型糖尿病和其他适应症有关的疾病。RBC提供75种HTS和IC50格式的蛋白酶测定。 Reaction Biology目前为蛋白酶分析提供以下服务:1,更大规模的HTS2,大规模单剂量,重复分析3,IC50分析 - 10剂量曲线拟合4,Ki测定5,定制分析开发名称                                                                                       同义词                                                                                数据ACE1血管紧张素转换酶ACE2ACE2N / AADAM10ADAM10N / ABACE1BACE1Calpain1Calpain1N / ACaspase 1Caspase 1Caspase 10Caspase 10Caspase 11Caspase 11Caspase 14Caspase 14Caspase 2Caspase 2Caspase 3Caspase 3Caspase 4Caspase 4Caspase 5Caspase 5Caspase 6Caspase 6Caspase 7Caspase 7Caspase 8Caspase 8Caspase 9Caspase 9组织蛋白酶B.组织蛋白酶B.N / A组织蛋白酶C.组织蛋白酶C.N / A组织蛋白酶D.组织蛋白酶D.组织蛋白酶E.组织蛋白酶E.组织蛋白酶G.组织蛋白酶G.N / A组织蛋白酶H.组织蛋白酶H.N / A组织蛋白酶L.组织蛋白酶L.N / A组织蛋白酶S.组织蛋白酶S.N / A组织蛋白酶V.组织蛋白酶V.N / A糜蛋白酶糜蛋白酶N / A糜蛋白酶糜蛋白酶N / A二肽基肽酶IV(DDP-IV)二肽基肽酶IV(DDP-IV)N / A二肽基肽酶IX(DPPIX)二肽基肽酶IX(DPPIX)N / A二肽基肽酶VIII(DPPVIII)二肽基肽酶VIII(DPPVIII)N / A弹性蛋白酶中性粒细胞弹性蛋白酶因子VIIa因子VIIaN / A因子Xa因子XaN / A因子XIa因子XIaN / AHIV蛋白酶HIV-1蛋白酶N / AKallikrein 1Kallikrein 1N / AKallikrein 12Kallikrein 12N / AKallikrein 13Kallikrein 13N / AKallikrein 14Kallikrein 14N / AKallikrein 5Kallikrein 5N / AKallikrein 7Kallikrein 7N / AMatriptase 2跨膜蛋白酶丝氨酸6MMP 1MMP 1MMP 10MMP 10N / AMMP 12MMP 12MMP 13MMP 13MMP 14MMP 14MMP 2MMP 2MMP 3MMP 3MMP 7MMP 7MMP 8MMP 8N / AMMP 9MMP 9脑啡肽酶脑啡肽酶N / A木瓜蛋白酶木瓜蛋白酶N / A血浆激肽释放酶血浆激肽释放酶N / A纤溶酶纤溶酶N / A蛋白酶A.蛋白酶A.N / A蛋白酶K.蛋白酶K.N / ATACETACE凝血酶凝血酶N / A胰蛋白酶胰蛋白酶N / A类胰蛋白酶b2类胰蛋白酶b2N / A类胰蛋白酶g1类胰蛋白酶g1N / A尿激酶尿激酶N / A需要咨询更多信息,请联系技术服务部   Jacky  Tel:18221539942    邮箱:jacky@rebiosci.net
  • PDE分析

    PDE分析

    PDE抑制剂阻断磷酸二酯酶(PDE)的五种亚型中的一种或多种,从而防止细胞内第二信使环腺苷一磷酸(cAMP)和环鸟苷一磷酸(cGMP)被各自的PDE亚型灭活。PDE抑制剂包括:咖啡因,己酮可可碱 - 用于治疗循环相关适应症,长春西汀 - 用于治疗脑血管疾病,依诺昔酮用于心力衰竭,ibudilast - 支气管扩张剂和西地那非 - 用于治疗勃起功能障碍。PDE抑制剂是或可能有用的其他适应症包括肺动脉高压,抗精神病药,COPD,鼻炎,肾痛和糖尿病。 Reaction Biology目前为PDE分析提供以下服务:1,更大规模的HTS 2,大规模单剂量,重复分析  3,IC50分析 - 10剂量曲线拟合 4,Ki测  5,定制分析开发名称                       同义词                                                                                                                                                           数据PDE10AcAMP和cAMP抑制cGMP 3',5'-环磷酸二酯酶10APDE1A钙/钙调蛋白依赖性3',5'-环核苷酸磷酸二酯酶1APDE1B钙/钙调蛋白依赖性3',5'-环核苷酸磷酸二酯酶1BPDE1C钙/钙调蛋白依赖性3',5'-环核苷酸磷酸二酯酶1CPDE2AcGMP依赖性3',5'-环磷酸二酯酶PDE3AcGMP抑制的3',5'-环磷酸二酯酶APDE3BcGMP抑制3',5'-环磷酸二酯酶B.PDE4AcAMP特异性3',5'-环磷酸二酯酶4APDE4BcAMP特异性3',5'-环磷酸二酯酶4BPDE4CcAMP特异性3',5'-环磷酸二酯酶4CPDE4DcAMP特异性3',5'-环磷酸二酯酶4DPDE5AcGMP特异性3',5'-环磷酸二酯酶PDE7A高亲和力cAMP特异性3',5'-环磷酸二酯酶7APDE8A高亲和力cAMP特异性和IBMX不敏感的3',5'-环磷酸二酯酶8APDE9A高亲和力cGMP特异性3',5'-环磷酸二酯酶9A需要咨询更多信息,请联系技术服务部   Jacky  Tel:18221539942    邮箱:jacky@rebiosci.net
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